BIOCOM/CRO Educational Seminar Series: Development of Poorly Water-Soluable Drug Candidates

February 23, 2012 (All day)
San Diego

Drug discovery programs frequently produce poorly water-soluble drug candidates which presents formulation scientists with technical challenges. Drug candidates that have low membrane permeability as well as poor aqueous solubility (BCS IV), are often poor candidates for development, unless the dose is expected to be very low. Drug candidates with good permeability and poor solubility (BCSII) can be successful depending on the performance of the formulated drug. Formulation options range from particle size reduction, formulation in solution as an amorphous system or lipid formulation or solid molecular dispersion.

Experts in formulation development, amorphous spray drying and hot melt extrusion will describe techniques for formulating poorly soluble compounds and discuss the advantages and disadvantages of each.

Moderator:
Timothy Scott, Pharmatek

Panelists:
Jeffrey Bibbs, Ph.D., Pharmatek
David Lyon, Ph.D., Bend Research
Blair West, Ph.D., Pharmaform

When: Thursday, February 23 from 8-10 a.m.
Where: BIOCOM Boardroom, 4510 Executive Drive, Plaza 7, San Diego 
Click here to register