Drug Solubility and Solubility Enhancement Technology
Bend Research is a leader in drug solubility and solubility enhancement. Our breadth of bioavailability enhancement technologies allows us to work collaboratively with our clients to advance compounds with a range of physicochemical properties and delivery challenges. Rather than an empirical exploration of a range of technologies, we use a fundamental, model-based approach to select the best technology for our clients’ compounds. We build on that approach in formulation optimization, process development, and scale-up to advance medicines to the clinic, and to the patient.
Bend Research has developed solubilization technologies with applicability at all stages of drug development from the discovery/development interface through commercial scale.
- Spray-Dried Dispersions (SDD)
- Hot-Melt Extrusion (HME)
- Solid NanoCrystalline Dispersions (SNCD)
- Spray-Dried NanoAdsorbate Technology (SDNA)
Our ability to formulate with minimal quantities of active means we can assist with lead selection by choosing the best compounds to progress at an early stage. Contact us to learn more.