Bioavailability Enhancement Webinar Series: Technology Selection for Enhancing Bioavailability

October 30, 2013 - 8:00am

 

David Vodak, Ph.D. presents this webinar entitled, "Technology Selection for Enhanced Bioavailability" which focuses on the rationale for selecting these enabling technologies based on a technology agnostic approach using a compound’s physical properties and product specifications.

Compounds that require bioavailability enhancement to achieve target absorption are increasingly common in current pipelines. These compounds must be paired with various technologies to enable progression.

This presentation will focus on the rationale for selecting these enabling technologies based on a technology agnostic approach using a compound’s physical properties (e.g., Tm, Tg, LogP) and product specifications (e.g., dose, pharmacokinetics, permeability). By using maps and guidances, it is possible to choose a lead formulation with little experimental work. This fundamental model-based approach reduces overall time to clinic vs. evaluating multiple technologies in a trial and error process.

With years of experience formulating these compounds, case studies will be presented that illustrate this process of technology and formulation selection based on using scientific fundamentals and not an empirical approach.

Presenter: David Vodak, Ph.D.

 

Topics: 
Bioavailability Enhancement