 Fundamental Science
Dedicating a portion of our research to fundamental
science enables Bend Research to be on the leading edge of novel
pharmaceutical-delivery technologies. Chris Babcock, Dwayne Friesen,
and Ron Beyerinck are some of the scientists
at Bend Research in the fundamental science group.
The focus of fundamental science at Bend Research is to develop new pharmaceutical-delivery
technologies, to improve the stability of existing formulations, and to
apply successful technologies to other pharmaceutical formulations. Bend
Research develops new technologies for a wide range of delivery routes such as
oral, ocular, parenteral, and pulmonary.
 Through material characterization and modeling, we have established an in-depth
understanding of how pharmaceutical-delivery technologies work.
A wide set of analytical tools is used for material characterization including
transmission electron microscopy (TEM), nuclear magnetic resonance (NMR),
powder x-ray diffraction (PXRD), differential scanning calorimetry
(DSC), and dissolution testing. Models are developed to test our understanding of the
technology during all phases of development.
For example, models are used to predict molecular properties, determine thermodynamic and
kinetic stability barriers, and predict mass transport of drug in the
body.
From knowledge gained through fundamental science, the
application of new technologies to promising compounds can be
streamlined. With an understanding of the material properties and the
desired delivery model of a new pharmaceutical formulation, we can apply sound
engineering principles to take the technology from the benchtop to the
commercial scale.
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