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Next Generation HPMC Capsules: Bioequivalence and Functional Performance

Date: 
January 19, 2016 - 8:00am
Short Description: 
Two-piece hard shell capsules made from hydroxypropyl methylcellulose (HPMC) are emerging as an alternative to conventional gelatin capsules for oral drug delivery when there is a physical incompatibility with gelatin. A new HPMC-polymer capsule without secondary gelling agents developed through a thermo-gelation process (Vcaps® Plus) has shown dissolution profiles similar to hard gelatin capsules, including pH and ionic independence.

Two-piece hard shell capsules made from hydroxypropyl methylcellulose (HPMC) are emerging as an alternative to conventional gelatin capsules for oral drug delivery when there is a physical incompatibility with gelatin. A new HPMC-polymer capsule without secondary gelling agents developed through a thermo-gelation process (Vcaps® Plus) has shown dissolution profiles similar to hard gelatin capsules, including pH and ionic independence.

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