Bioavailability Enhancement

Drawdown of Floating Solids in Stirred Tanks: Scale-up Study using CFD Modeling

Date: 
October 14, 2011
Short Description: 
This work shows development of a scale up correlation using computational fluid dynamic (CFD) simulations for floating solids drawdown operation in stirred tanks. Discrete phase modeling (DPM) simulations were used in conjunction with the lab scale experimental measurements to develop a semi-empirical correlation for the prediction of rate of drawdown of floating solid particles.

 

Waghmare, Y., R. Falk, L. Graham, and V. Koganti, “Drawdown of Floating Solids in Stirred Tanks: Scale-up Study using CFD Modeling” Int. J. Pharm., 418:2(2011)243-253.

 

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