Bioavailability Enhancement

Fundamentals of Spray-Dried Dispersion Technology

April 7, 2016 - 9:30am
Short Description: 
Current estimates indicate that more than 70% of new chemical entities require solubilization technology to achieve efficacious plasma exposure. Amorphous solid dispersion technology is a leading approach to improve solubility and dissolution rate of these insoluble compounds by providing a supersaturated concentration of drug in the gastrointestinal environment, which often translates to rapid absorption and improved bioavailability. Amorphous solid dispersions are typically prepared by using hot-melt extrusion or spray drying processes. This webinar will focus on the fundamentals of formulating and processing of spray-dried dispersions, including stability assessment, in-vitro performance, and downstream manufacturability.


April 7, 2016 | 12:30pm EDT/9:30am PDT


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