Modified & Targeted Release

Osmotic Capsules: A Universal Oral, Controlled-Release Drug Delivery Dosage Form

Date: 
June 10, 2011
Short Description: 
An osmotic, oral, controlled-release capsule is described. This capsule provides drug delivery at fixed delivery rates (T80% = 6 or 14 h) independent of drug properties (e.g., solubility) or drug loading, thereby allowing rapid development of investigational or commercial drugs, especially for proof-of-concept type clinical studies.

 

Waterman, K.C., G.S. Goeken, S.J. Konagurthu, M.D., Likar, B.C. MacDonald, N. Mahajan, and V. Swaminathan, “Osmotic Capsules: A Universal Oral, Controlled-Release Drug Delivery Dosage Form,” J. of Controlled Release, 152:2(2011)264-269. Also published on Science Direct, February 9, 2011

 

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