Biotherapeutics / Bioprocessing

Dielectric Spectroscopy (DS)

Short Description: 
The bioprocessing industry demands an online monitoring technique that accurately provides real-time cell-level information and guidance in situ, in the bioreactor. Of particular importance is the ability to perform online monitoring of viable cell volume (VCV), which is essential to the development and control of bioprocesses. The availability of dielectric spectroscopy (DS) probes has enabled successful adoption of this technology as a key noninvasive method to measure VCV for cell-culture processes. Bend Research has developed methods incorporating DS measurements and the reduction of large DS data sets to obtain measurements of both VCV, as well as cell state throughout the bioreactor growth curve.
Attached File(s): 

The bioprocessing industry demands an online monitoring technique that accurately provides real-time cell-level information and guidance in situ, in the bioreactor. Of particular importance is the ability to perform online monitoring of viable cell volume (VCV), which is essential to the development and control of bioprocesses. The availability of dielectric spectroscopy (DS) probes has enabled successful adoption of this technology as a key noninvasive method to measure VCV for cell-culture processes.

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